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A sweep of earth’s virome reveals host-guided viral protein structural mimicry; with implications for human disease

2020-06-18

Abstract excerpt

<h4>SUMMARY</h4> Viruses deploy an array of genetically encoded strategies to coopt host machinery and support viral replicative cycles. Molecular mimicry, manifested by structural similarity between viral and endogenous host proteins, allow viruses to harness or disrupt cellular functions including nucleic acid metabolism and modulation of immune responses. Here, we use protein structure similarity to scan for v...

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Literature Corpus work
46727d05-7f5c-5b2d-8308-4fb9493cb8b6
DOI
10.1101/2020.06.18.159467
Open publication

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A sweep of earth’s virome reveals host-guided viral protein structural mimicry; with implications for human diseaseDOI 10.1101/2020.06.18.159467
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