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Identifying novel antiviral defences against VSV and HIV-1

2019-01-01

Abstract excerpt

Mammalian cells encode an arsenal of antiviral defences, which can be deployed following sensing of an invading pathogen. These cell autonomous defences are stimulated by interferon (IFN) signalling which activates the expression of interferon-stimulated genes (ISGs) that encode numerous antiviral proteins and can alter the thermal landscape of the host. These ISGs can constrain virus replication, transmission and...

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Literature Corpus work
7cb29940-ea0f-59a2-b29d-20a7e708fa98
DOI
10.5525/gla.thesis.76771
Open publication

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Identifying novel antiviral defences against VSV and HIV-1DOI 10.5525/gla.thesis.76771
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