Article

The utility of CRISPR activation as a platform to identify interferon stimulated genes with anti-viral function

2023-08-28

Abstract excerpt

Interferon Stimulated Genes (ISGs) play key roles in the control of viral replication and dissemination. Understanding this dynamic relationship between the pathogen and host is critical to our understanding of viral life-cycles and development of potential novel anti-viral strategies. Traditionally, plasmid based exogenous prompter driven expression of ISGs has been used to investigate anti-viral ISG function, ho...

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Literature Corpus work: dc2da807-7b1b-5154-ab0b-f9a5e99f86de
DOI: 10.1101/2023.08.28.555046

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