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Article

Temperature elevation synergises with and enhances the type-I IFN-mediated restriction of MPXV

2023-09-29

Abstract excerpt

Fever is an evolutionary conserved host pro-inflammatory immune response that governs the regulation of multiple biological processes to control the outcome of infection. In January 2022, the World Health Organization (WHO) reported a global outbreak in mpox cases with a high incidence of human-to-human transmission. A frequent prodromal symptom of monkeypox virus (MPXV) infection is fever, with a febrile temperat...

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Literature Corpus work
b0a43aa0-3d58-5021-aa57-10023b105d40
DOI
10.1101/2023.09.29.560106
Open publication

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