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Article

CHD7 regulates cardiovascular development through ATP-dependent and -independent activities.

Proceedings of the National Academy of Sciences of the United States of America - 17 Nov 2020

Yan Shun, Thienthanasit Rassarin, Chen Dongquan, Engelen Erik, Brühl Joanna, Crossman David K, Kesterson Robert, Wang Qin, Bouazoune Karim, Jiao Kai

Abstract excerpt

CHD7 encodes an ATP-dependent chromatin remodeling factor. Mutation of this gene causes multiple developmental disorders, including CHARGE (Coloboma of the eye, Heart defects, Atresia of the choanae, Retardation of growth/development, Genital abnormalities, and Ear anomalies) syndrome, in which conotruncal anomalies are the most prevalent form of heart defects. How CHD7 regulates conotruncal development remains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33127760
DOI: 10.1073/pnas.2005222117
PMCID: PMC7682373

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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