Article

MicroRNA miR-92b-3p regulation of a cardiovascular gene regulatory network in the developing branchial arches

2024-07-29

Abstract excerpt

<h4>ABSTRACT</h4> Vertebrate branchial arches (BAs) are a developmental paradigm, undergoing coordinated differentiation and morphogenesis to form various adult derivative tissues. MicroRNAs can strengthen gene regulatory networks (GRNs) to promote developmental stability. To interrogate the contribution of microRNAs to BA development, we generated a novel microRNA-sequencing dataset from mouse BAs. We identified...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7ca525c7-cf8c-5cf6-b797-05f1fcabdfe4
DOI: 10.1101/2024.07.28.605500

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MicroRNA miR-92b-3p regulation of a cardiovascular gene regulatory network in the developing branchial archesDOI 10.1101/2024.07.28.605500Read

Single-cell RNA-seq of the Developing Cardiac Outflow Tract Reveals Convergent Development of the Vascular Smooth Muscle Cells at the Base of the Great ArteriesSemantic proximity Read

Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo.Semantic proximity Read

Spotlight on Isl1: A Key Player in Cardiovascular Development and DiseasesSemantic proximity Read

Single cell transcriptomics uncovers a non-autonomous <i>Tbx1</i> -dependent genetic program controlling cardiac neural crest cell deployment and progressionSemantic proximity Read

A cell atlas of the developing human outflow tract of the heart and its adult aortic valve derivativesSemantic proximity Read

Fate of developmental mechanisms of myocardial plasticity in the postnatal heartSemantic proximity Read

Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development.Semantic proximity Read

Smarcd3b and Gata5 promote a cardiac progenitor fate in the zebrafish embryoSemantic proximity Read

Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial–mesenchymal transition via Bmp2Semantic proximity Read

Identification of a Tbx1/Tbx2/Tbx3 genetic pathway governing pharyngeal and arterial pole morphogenesis.Semantic proximity Read

Ankrd11, a chromatin regulator and a KBG syndrome risk gene, is a critical regulator of cardiac neural crest cell biology and heart developmentSemantic proximity Read

The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart functionSemantic proximity Read