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Article

Smarcd3b and Gata5 promote a cardiac progenitor fate in the zebrafish embryo

30 Jun 2011

Abstract excerpt

Development of the heart requires recruitment of cardiovascular progenitor cells (CPCs) to the future heart-forming region. CPCs are the building blocks of the heart, and have the potential to form all the major cardiac lineages. However, little is known regarding what regulates CPC fate and behavior. Activity of GATA4, SMARCD3 and TBX5 - the `cardiac BAF' (cBAF) complex, can promote myocardial differentiation in...

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PMID: 21715426
DOI: 10.1242/dev.064279

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