Article
Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development.
Proceedings of the National Academy of Sciences of the United States of America - 29 Jan 2013
Li Wei, Xiong Yiqin, Shang Ching, Twu Karen Y, Hang Calvin T, Yang Jin, Han Pei, Lin Chieh-Yu, Lin Chien-Jung, Tsai Feng-Chiao, Stankunas Kryn, Meyer Tobias, Bernstein Daniel, Pan Minggui, Chang Ching-Pin
Abstract excerpt
Development of the cerebral vessels, pharyngeal arch arteries (PAAs). and cardiac outflow tract (OFT) requires multipotent neural crest cells (NCCs) that migrate from the neural tube to target tissue destinations. Little is known about how mammalian NCC development is orchestrated by gene programming at the chromatin level, however. Here we show that Brahma-related gene 1 (Brg1), an ATPase subunit of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.