Article

APOE4 rat model of Alzheimer’s disease: sex differences, genetic risk and diet

2024-05-14

Abstract excerpt

<title>Abstract</title> <p>The strongest genetic risk factor for Alzheimer’s disease (AD) is the Ɛ4 allele of apolipoprotein E (<italic>ApoE ɛ4</italic>). A high fat diet also adds to the risk of dementia and AD. In addition, there are sex differences as women carriers have a higher risk of an earlier onset and rapid decline in memory than men. The present study looked at the effect of the genetic risk of <italic...

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Literature Corpus work: 7c95da2f-c5a3-5d7c-af45-60a07dac2f50
DOI: 10.21203/rs.3.rs-4339838/v1

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