Back to search

Article

Population Genetic Analysis of Plasmodium falciparum Circumsporozoite Protein in Two Distinct Ecological Regions in Ghana

2020-11-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Extensive genetic diversity in the<bold> </bold><italic>Plasmodium falciparum</italic> circumsporozoite protein (PfCSP) is a major contributing factor to the moderate efficacy of the RTS,S/AS01 vaccine. The transmission intensity and rates of recombination within and between populations influence the extent of its genetic diversity. Understanding the extent and d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7c858879-2ce5-5ad7-b490-022a644830fb
DOI
10.21203/rs.3.rs-52164/v3
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Population Genetic Analysis of&nbsp;Plasmodium falciparum&nbsp;Circumsporozoite Protein in Two Distinct Ecological Regions in GhanaDOI 10.21203/rs.3.rs-52164/v3
Population genetic analysis of the Plasmodium falciparum circumsporozoite protein in two distinct ecological regions in Ghana.Semantic proximity
Genetic polymorphism of Plasmodium falciparum circumsporozoite protein on Bioko Island, Equatorial Guinea and global comparative analysisSemantic proximity
Genetic analysis of the circumsporozoite gene in Plasmodium falciparum isolates from Cameroon: Implications for efficacy and deployment of RTS,S/AS01 vaccine.Semantic proximity
Genetic polymorphism of Plasmodium falciparum circumsporozoite protein on Bioko Island, Equatorial Guinea and global comparative analysisSemantic proximity
Genetic diversity of Plasmodium falciparum isolates from uncomplicated malaria cases in Ghana over a decade.Semantic proximity
Protein interaction analysis of <i>Plasmodium falciparum</i> circumsporozoite protein variants with human immunoproteins explains RTS,S vaccine efficacy in GhanaSemantic proximity
Genetic variations of Plasmodium falciparum circumsporozoite protein and the impact on interactions with human immunoproteins and malaria vaccine efficacy.Semantic proximity
Comparison of genomic signatures of selection on Plasmodium falciparum between different regions of a country with high malaria endemicity.Semantic proximity
Genetic diversity in the Plasmodium falciparum next-generation blood stage vaccine candidate antigen PfCyRPA in Senegal.Semantic proximity
Extreme Genetic Diversity and Signatures of Balancing Selection in Plasmodium vivax Blood-Stage Antigens.Semantic proximity
Population structure and diversity of Plasmodium falciparum in children with asymptomatic malaria living in different ecological zones of Ghana.Semantic proximity
Plasmodium falciparum AMA1 and CSP antigen diversity in parasite isolates from southern Ghana.Semantic proximity
Select a neighboring publication to make it the new centre.