Article
Comparison of genomic signatures of selection on Plasmodium falciparum between different regions of a country with high malaria endemicity.
BMC genomics - 16 Jul 2015
Duffy Craig W, Assefa Samuel A, Abugri James, Amoako Nicholas, Owusu-Agyei Seth, Anyorigiya Thomas, MacInnis Bronwyn, Kwiatkowski Dominic P, Conway David J, Awandare Gordon A
Abstract excerpt
BACKGROUND: Genome wide sequence analyses of malaria parasites from widely separated areas of the world have identified contrasting population structures and signatures of selection. To compare relatively closely situated but ecologically contrasting regions within an endemic African country, population samples of Plasmodium falciparum clinical isolates were collected in Ghana from Kintampo in the central...
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