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Machine learning identifies shared blood transcriptional biomarkers and immune correlates across antiphospholipid syndrome and systemic sclerosis

2026-01-22

Abstract excerpt

Antiphospholipid syndrome (APS) and systemic sclerosis (SSc) are immune-mediated multisystem autoimmune diseases with distinct clinical phenotypes but overlapping pathogenic themes, including immune dysregulation, chronic inflammation, and endothelial injury. Using peripheral blood transcriptome datasets from the Gene Expression Omnibus (GSE102215: 9 APS/9 controls; GSE231691: 49 SSc/18 controls), we performed dif...

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Literature Corpus work
7c64997c-d1a9-5de8-be92-592cb87fedd1
DOI
10.64898/2026.01.20.26344459
Open publication

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Machine learning identifies shared blood transcriptional biomarkers and immune correlates across antiphospholipid syndrome and systemic sclerosisDOI 10.64898/2026.01.20.26344459
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