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Prioritization of Diagnostic and Prognostic Biomarkers for Lupus Nephritis Based on Integrated Bioinformatics Analyses

8 Oct 2021

Abstract excerpt

Lupus nephritis (LN) is an important driver of end-stage renal disease (ESRD). However, few biomarkers are available for evaluating the diagnosis and prognosis of LN. For this study, we downloaded microarray data of multiple LN expression profiles from the GEO database. We used the WGCNA and R limma packages to identify LN hub genes and differentially-expressed genes (DEGs). We identified nine co-DEGs in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34692653
DOI: 10.3389/fbioe.2021.717234

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