Article

SUV39H1 Preserves Cancer Stem Cell Chromatin State and Properties in Glioblastoma

2024-08-19

Abstract excerpt

Of the more than 100 types of brain cancer, glioblastoma (GBM) is the deadliest. As GBM stem cells (GSCs) are considered to be responsible for therapeutic resistance and tumor recurrence, effective targeting and elimination of GSCs could hold promise for preventing GBM recurrence and achieving potential cures. We show here that SUV39H1 , which encodes a histone-3, lysine-9 methyltransferase, plays a critical role...

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Literature Corpus work: 7c2d1510-408e-5b79-a194-493bea61c81e
DOI: 10.1101/2024.08.15.607856

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