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Comparison between a Luminex-based multiplex kit with a sequence-specific oligonucleotide probe and next-generation sequencing for the detection of POLE oncogenic mutations in endometrial cancer

2024-12-10

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<title>Abstract</title> <p><bold>Objective: </bold>In endometrial cancer,<bold> </bold>detection of oncogenic mutations in the polymerase epsilon (<italic>POLE</italic>) gene is crucial for accurate staging according to the 2023 International Federation of Gynecology and Obstetrics classification and for minimizing overtreatment. However, <italic>POLE</italic>sequencing is expensive, time-consuming, and often ina...

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Literature Corpus work
7bfd1eb3-f2cc-583b-aaa9-aaed51f63e70
DOI
10.21203/rs.3.rs-5540131/v1
Open publication

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Comparison between a Luminex-based multiplex kit with a sequence-specific oligonucleotide probe and next-generation sequencing for the detection of POLE oncogenic mutations in endometrial cancerDOI 10.21203/rs.3.rs-5540131/v1
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