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Article

Tumor-infiltrating lymphocytes and POLE mutation in endometrial carcinoma.

Gynecologic oncology - 1 May 2021

Raffone Antonio, Travaglino Antonio, Raimondo Diego, Boccellino Maria Pia, Maletta Manuela, Borghese Giulia, Casadio Paolo, Insabato Luigi, Mollo Antonio, Zullo Fulvio, Seracchioli Renato

Abstract excerpt

BACKGROUND: Polymerase-ε (POLE)-mutated endometrial carcinomas (ECs) have displayed an increased number of tumor-infiltrating lymphocytes (TIL) compared to POLE-wild-type ECs. However, it is unclear if TIL may aid in identifying POLE-mutated ECs when molecular data are unavailable. The identification of a POLE mutation surrogate may be crucial to translate TCGA/ProMisE risk assessment in the clinical practice....

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Identifiers

PMID: 33715893
DOI: 10.1016/j.ygyno.2021.02.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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