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The link between the<i>ANPEP</i>gene and type 2 diabetes mellitus may be mediated by the disruption of glutathione metabolism and redox homeostasis

2024-03-18

Abstract excerpt

Aminopeptidase N (ANPEP), a membrane-associated ectoenzyme, has been identified as a susceptibility gene for type 2 diabetes (T2D) by genome-wide association and transcriptome studies; however, the mechanisms by which this gene contributes to disease pathogenesis remain unclear. The aim of this study was to determine the comprehensive contribution of ANPEP polymorphisms to T2D risk and annotate the underlying mech...

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Identifiers and source

Literature Corpus work
d16a033f-f0fa-53b4-9613-dd8594c22a94
DOI
10.1101/2024.03.16.24304385
Open publication

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The link between the<i>ANPEP</i>gene and type 2 diabetes mellitus may be mediated by the disruption of glutathione metabolism and redox homeostasisDOI 10.1101/2024.03.16.24304385
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