Article

Optimizing canine T cell activation, expansion, and transduction

2025-04-30

Abstract excerpt

Dogs are becoming an important model for human cancers, and successfully troubleshooting issues with genetically modified T cell immunotherapy for round cell and solid neoplasms in dogs provides a unique opportunity to improve efficacy, safety, and affordability for humans as well. Unfortunately, T cell activation in dogs for optimal viral transduction has not been determined, restricting advancements in canine T...

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Literature Corpus work: 7bda9198-5c38-528b-8c3f-60137d9ef8a8
DOI: 10.1101/2025.04.26.650803

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