Article
Advancing CAR T-cell therapies: Preclinical insights and clinical translation for hematological malignancies
12 Sept 2024
Abstract excerpt
Chimeric antigen receptor (CAR) T-cell therapy has achieved significant success in achieving durable and potentially curative responses in patients with hematological malignancies. CARs are tailored fusion proteins that direct T cells to a specific antigen on tumor cells thereby eliciting a targeted immune response. The approval of several CD19-targeted CAR T-cell therapies has resulted in a notable surge in...
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