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Direct comparison of canine and human immune responses using transcriptomic and functional analyses

26 Jan 2024

Abstract excerpt

The canine spontaneous cancer model is increasingly utilized to evaluate new combined cancer immunotherapy approaches. While the major leukocyte subsets and phenotypes are closely related in dogs and humans, the functionality of T cells and antigen presenting cells in the two species has not been previously compared in detail. Such information would be important in interpreting immune response data and evaluating...

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PMID: 38272935
DOI: 10.1038/s41598-023-50340-9

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