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Article

Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients

2021-07-31

Abstract excerpt

<h4>Background: </h4> Cancer is the leading cause of death in the geriatric dog population. Currently, the use of immune checkpoint inhibitors (ICIs) such as anti-CTLA4 antibodies has markedly improved the prognosis of several cancers in their advanced stages. However, ICIs targeting CTLA4 blockade to treat canine cancer patients are yet to define. In this study, we sought to develop, characterize and assess wheth...

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Literature Corpus work
4a149638-ef20-5959-97e3-eb254b0131d0
DOI
10.21203/rs.3.rs-765466/v1
Open publication

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Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patientsDOI 10.21203/rs.3.rs-765466/v1
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