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Ikaros Regulates microRNA Networks in Acute Lymphoblastic Leukemia

2022-08-17

Abstract excerpt

The hematopoietic transcription factor Ikaros (IKZF1) regulates normal B cell development and functions as a tumor suppressor in precursor B cell acute lymphoblastic leukemia (B-ALL). MicroRNAs (miRNAs) are small regulatory RNAs that through post-transcriptional gene regulation play critical roles in intracellular processes including cell growth in cancer. However, the role of Ikaros in the regulation of miRNA exp...

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Literature Corpus work
7bcbec5d-a214-5c04-8238-b3c6889d2aa8
DOI
10.20944/preprints202208.0323.v1
Open publication

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Ikaros Regulates microRNA Networks in Acute Lymphoblastic LeukemiaDOI 10.20944/preprints202208.0323.v1
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