Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II in leukemia

7 Dec 2015

Abstract excerpt

IKZF1 ( Ikaros ) encodes a DNA-binding protein that acts as a master regulatory of hematopoiesis and a tumor suppressor in acute lymphoblastic leukemia (ALL). 1 , 2 , 3 , 4 The deletion and/or mutation of Ikaros is associated with the development of B-cell acute lymphoblastic leukemia (B-ALL) with poor outcome. 5 , 6 , 7 , 8 , 9 , 10 , 11 Ikaros directly associates with components of the histone deacetylase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Acute Myeloid Leukemia Research
Share to Childhood Cancer Survivors' Quality of Life

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26639180
DOI: 10.1038/leu.2015.331

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II in leukemiaPMID 26639180Read ↗

Cellular signaling and epigenetic regulation of gene expression in leukemiaSemantic proximity Read ↗

Ikaros and Tumor Suppression in Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcomeSemantic proximity Read ↗

Ikaros Regulates microRNA Networks in Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

IKZF1 in acute lymphoblastic leukemia: the rise before the fall?Semantic proximity Read ↗

Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre–B ALLSemantic proximity Read ↗

Ikaros Regulates microRNA Networks in Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

Critical roles of Ikaros and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

IKAROS Deletions Dictate a Unique Gene Expression Signature in Patients with Adult B-Cell Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Conserved helical motifs in the IKZF1 disordered region mediate NuRD interaction and transcriptional repressionSemantic proximity Read ↗

Conserved helical motifs in the Ikaros IDR mediate NuRD interaction and transcriptional repressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.