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Article

Regulator of myeloid differentiation and function: The secret life of Ikaros

1 Jan 2011

Abstract excerpt

Ikaros (also known as Lyf-1) was initially described as a lymphoid-specific transcription factor. Although Ikaros has been shown to regulate hematopoietic stem cell renewal, as well as the development and function of cells from multiple hematopoietic lineages, including the myeloid lineage, Ikaros has primarily been studied in context of lymphoid development and malignancy. This review focuses on the role of...

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PMID: 21765977
DOI: 10.4331/wjbc.v2.i6.119

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