Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ikaros and Tumor Suppression in Acute Lymphoblastic Leukemia

1 Jan 2011

Abstract excerpt

The Ikzf1 gene encodes Ikaros-a DNA-binding zinc finger protein. Ikaros functions as a regulator of gene expression and chromatin remodeling. The biological roles of Ikaros include regulating the development and function of the immune system and acting as a master regulator of hematopoietic differentiation. Genomic profiling studies identified Ikzf1 as an important tumor suppressor in acute lymphoblastic leukemia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Acute Myeloid Leukemia Research
Share to Childhood Cancer Survivors' Quality of Life

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22150303
DOI: 10.1615/critrevoncog.v16.i1-2.20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ikaros and Tumor Suppression in Acute Lymphoblastic LeukemiaPMID 22150303Read ↗

[Effect of Ikaros in B Cell Acute Lymphoblastic Leukemia].Semantic proximity Read ↗

Role of Ikaros in T-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

Ikaros Regulates microRNA Networks in Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

IKZF1 in acute lymphoblastic leukemia: the rise before the fall?Semantic proximity Read ↗

Ikaros Regulates microRNA Networks in Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre–B ALLSemantic proximity Read ↗

Ikaros and leukaemia.Semantic proximity Read ↗

Ikaros gene expression and leukemia.Semantic proximity Read ↗

Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

Critical roles of Ikaros and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

Genetic inactivation of Ikaros is a rare event in human T-ALL.Semantic proximity Read ↗

Regulator of myeloid differentiation and function: The secret life of IkarosSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.