Article

Involvement of multiple loci on chromosome 3 in renal cell cancer development

1997-06-01

Abstract excerpt

In renal cell carcinoma (RCC), mostly occurring as sporadic cases, the short arm of chromosome 3 is a frequent target of deletion events. Taking into account cytological classifications of RCC, the deletions appear to be characteristic of clear cell or nonpapillary RCC only. This subtype constitutes most sporadic RCC and RCC as part of the Von Hippel-Lindau disease caused by germline mutations of VHL at 3p25. In a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7bb79a15-e7d7-5003-8923-1ef4c6cbcc18
DOI: 10.1002/(sici)1098-2264(199706)19:2<59::aid-gcc1>3.0.co;2-z

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Involvement of multiple loci on chromosome 3 in renal cell cancer developmentDOI 10.1002/(sici)1098-2264(199706)19:2<59::aid-gcc1>3.0.co;2-zRead

Involvement of multiple loci on chromosome 3 in renal cell cancer developmentSemantic proximity Read

Involvement of 3p deletions in sporadic and hereditary forms of renal cell carcinoma.Semantic proximity Read

Molecular study of a new family with hereditary renal cell carcinoma and a translocation t(3;8)(p13;q24.1).Semantic proximity Read

Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes.Semantic proximity Read

[Development of human renal cell carcinoma (RCC)--the responsible genes for the development of hereditary and sporadic human RCCs].Semantic proximity Read

Genetic alterations in sporadic renal-cell carcinoma: molecular analyses of tumor suppressor gene harboring chromosomal regions 3p, 5q, and 17p.Semantic proximity Read

Understanding familial and non-familial renal cell cancerSemantic proximity Read

Molecular genetic investigation of sporadic renal cell carcinoma: analysis of allele loss on chromosomes 3p, 5q, 11p, 17 and 22.Semantic proximity Read

Mutation of the VHL gene is associated exclusively with the development of non-papillary renal cell carcinomas.Semantic proximity Read

Analysis of multiple renal cell adenomas and carcinomas suggests allelic loss at 3p21 to be a prerequisite for malignant development.Semantic proximity Read

Association of a novel constitutional translocation t(1q;3q) with familial renal cell carcinoma.Semantic proximity Read

Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR.Semantic proximity Read