Article

Agonism of mosquito and human transient receptor potential ankyrin 1 (TRPA1) channels by the natural drimane sesquiterpene cinnamodial

2025-12-11

Abstract excerpt

TRPA1 channels are multi-modal receptors in animals for sensing noxious physical and chemical factors. They are considered promising biochemical targets for developing repellents of arthropod disease vectors and drugs to treat a variety of medical conditions including pain, inflammation, and itch. Recently, we discovered that cinnamodial (CDIAL), a natural drimane sesquiterpene produced by the medicinal plant Cin...

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Identifiers and source

Literature Corpus work: 7baea42e-537e-51d0-adc3-e4f4a8740661
DOI: 10.64898/2025.12.09.693172

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