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Article

Distinct cryo-EM Structure of α-synuclein Filaments derived by Tau

2021-01-03

Abstract excerpt

Recent structural studies of ex vivo amyloid filaments extracted from human patients demonstrated that the ex vivo filaments associated with different disease phenotypes adopt diverse molecular conformations distinct from those in vitro amyloid filaments. A very recent cryo-EM structural study also revealed that ex vivo α-synuclein filaments extracted from multiple system atrophy (MSA) patients adopt quite distinc...

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Literature Corpus work
7b60744d-3e4e-5776-887e-0e0d5b42ef07
DOI
10.1101/2020.12.31.424989
Open publication

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Distinct cryo-EM Structure of α-synuclein Filaments derived by TauDOI 10.1101/2020.12.31.424989
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