Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complete-proteome mapping of human influenza A adaptive mutations: implications for human transmissibility of zoonotic strains.

PloS one - 3 Feb 2010

Miotto Olivo, Heiny A T, Albrecht Randy, García-Sastre Adolfo, Tan Tin Wee, August J Thomas, Brusic Vladimir

Abstract excerpt

BACKGROUND: There is widespread concern that H5N1 avian influenza A viruses will emerge as a pandemic threat, if they become capable of human-to-human (H2H) transmission. Avian strains lack this capability, which suggests that it requires important adaptive mutations. We performed a large-scale c...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birds
Share to Databases, Protein
Share to Influenza A virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A Virus, H5N1 Subtype

Share to Influenza, Human

Share to Influenza in Birds

Share to Orthomyxoviridae Infections

Share to Zoonoses

Source

Open in PubMed Open full text

Identifiers

PMID: 20140252
DOI: 10.1371/journal.pone.0009025
PMCID: PMC2815782

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20140252-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complete-proteome mapping of human influenza A adaptive mutations: implications for human transmissibility of zoonotic strains.PMID 20140252Read ↗

Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysisSemantic proximity Read ↗

Adaptation of pandemic H2N2 influenza A viruses in humans.Semantic proximity Read ↗

Comprehensive mapping of adaptation of the avian influenza polymerase protein PB2 to humansSemantic proximity Read ↗

Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses.Semantic proximity Read ↗

Comprehensive mapping of avian influenza polymerase adaptation to the human hostSemantic proximity Read ↗

Avian Influenza H7N9 Virus Adaptation to Human Hosts.Semantic proximity Read ↗

Decoding non-human mammalian adaptive signatures of 2.3.4.4b H5N1 to assess its human adaptive potentialSemantic proximity Read ↗

Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin.Semantic proximity Read ↗

In Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses.Semantic proximity Read ↗

Characterization of H5N1 Influenza Virus Quasispecies with Adaptive Hemagglutinin Mutations from Single-Virus Infections of Human Airway Cells.Semantic proximity Read ↗

Adaptation of H9N2 Influenza Viruses to Mammalian Hosts: A Review of Molecular Markers.Semantic proximity Read ↗

Decoding non-human mammalian adaptive signatures of 2.3.4.4b H5N1 to assess its human adaptive potentialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.