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Genomic subtypes inferred from clinical sequencing provide significant prognostic stratification in metastatic breast cancer

2026-08-17

Abstract excerpt

<h4>Purpose</h4> The 11 Integrative Cluster (IntClust) genomic subtypes of breast cancer have both prognostic and predictive value but require integrated DNA copy-number and gene expression profiling, which are not routinely used in clinical care. We tested whether IntClust could be inferred from clinical DNA targeted gene panel sequencing alone and whether the assignments stratify overall survival (OS) in a cont...

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Literature Corpus work
7b2ca8c3-8598-5b71-9cc0-425aef483b5c
DOI
10.64898/2026.08.15.26360497
Open publication

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Genomic subtypes inferred from clinical sequencing provide significant prognostic stratification in metastatic breast cancerDOI 10.64898/2026.08.15.26360497
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