Article

Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium

2022-02-14

Abstract excerpt

<h4>Objective</h4> Methotrexate (MTX) is an anchor drug for rheumatoid arthritis (RA) treatment; however, the exact mechanisms by which MTX improves RA activity are still debatable. This study aimed to understand the roles of molecules whose expression is affected by MTX in RA patients and find novel therapeutic targets. <h4>Methods</h4> CD4 + T cells from 28 treatment naïve RA patients before and 3 months afte...

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Literature Corpus work: 7af052a9-256c-5d1c-b7c4-1e232dec06d6
DOI: 10.1101/2022.02.12.480222

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