Article
The role of semaphorins in immune responses and autoimmune rheumatic diseases.
Nature reviews. Rheumatology - 1 Jan 2018
Nishide Masayuki, Kumanogoh Atsushi
Abstract excerpt
Semaphorins have a well-characterized role in guiding axon repulsion during development; however, the important contribution of these proteins in immunity is becoming increasingly clear. Immunoregulatory semaphorins, termed 'immune semaphorins', have roles in regulating immune cell activation, differentiation, mobility and migration. These proteins are also intimately associated with the pathogenesis of...
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