Article

Altered Network Efficiency in Isolated REM Sleep Behaviour Disorder: A Multicentric Study

2025-07-10

Abstract excerpt

Isolated REM sleep behavior disorder (iRBD), a prodromal synucleinopathy, generally precedes Parkinson’s disease (PD) or dementia with Lewy bodies (DLB). While disruptions in structural brain connectivity have been reported in these diseases, their presence in prodromal phases such as iRBD remains unclear. In this cross-sectional study, we analysed diffusion MRI in a large multicentric dataset (198 iRBD, 174 contr...

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Literature Corpus work: 7aeb62f1-faf7-5b91-8b1e-ead4244533b7
DOI: 10.1101/2025.07.08.25331130

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