Article

MCL-1 regulates cellular transitions during oligodendrocyte development

2024-12-21

Abstract excerpt

Oligodendrocytes are the myelinating cells of the central nervous system. Regulation of the early stages of oligodendrocyte development is critical to the function of the cell. Specifically, myelin sheath formation is an energetically demanding event that requires precision, as alterations may lead to dysmyelination. Recent work has established that fatty acid β-oxidation is required for the function of oligodendr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7ab38a53-134c-50ee-916c-c2d91f116745
DOI: 10.1101/2024.12.20.629796

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MCL-1 regulates cellular transitions during oligodendrocyte developmentDOI 10.1101/2024.12.20.629796Read

Oligodendrocyte Development and Myelination in Neurodevelopment: Molecular Mechanisms in Health and DiseaseSemantic proximity Read

Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degenerationSemantic proximity Read

Dying oligodendrocytes persist without mitochondriaSemantic proximity Read

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathwaysSemantic proximity Read

BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytesSemantic proximity Read

Environmental and Nutritional “Stressors” and Oligodendrocyte Dysfunction: Role of Mitochondrial and Endoplasmatic Reticulum ImpairmentSemantic proximity Read

How to make an oligodendrocyte.Semantic proximity Read

Musashi1 RNA-binding protein regulates oligodendrocyte lineage cell differentiation and survival.Semantic proximity Read

Myelination and oligodendrocyte functions in psychiatric diseases.Semantic proximity Read

Stem Cell-Derived Oligodendroglial Cells for Therapy in Neurological Diseases.Semantic proximity Read

A critical role for miR-184 in the fate determination of oligodendrocytesSemantic proximity Read

Inhibition of mitochondrial function induces an integrated stress response in oligodendrogliaSemantic proximity Read