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Article

A critical role for miR-184 in the fate determination of oligodendrocytes

29 Mar 2019

Abstract excerpt

BACKGROUND: New insights on cellular and molecular aspects of both oligodendrocyte (OL) differentiation and myelin synthesis pathways are potential avenues for developing a cell-based therapy for demyelinating disorders comprising multiple sclerosis. MicroRNAs (miRNA) have broad implications in all aspects of cell biology including OL differentiation. MiR-184 has been identified as one of the most highly enriched...

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PMID: 30922384
DOI: 10.1186/s13287-019-1208-y

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