Article

Dying oligodendrocytes persist without mitochondria

2026-01-22

Abstract excerpt

<h4>ABSTRACT</h4> Myelin is an insulating, multi-layered membrane that supports axonal integrity and neural communication. Different stressors impair myelinating oligodendrocytes, leading to demyelination, inflammation, and neurodegeneration. The intracellular processes underlying oligodendrocyte degeneration and death are unclear. Here, using optically targeted DNA damage that causes single-cell demyelination, w...

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Literature Corpus work: 3a6c209d-e982-52e4-8e0a-3bb7b618085f
DOI: 10.64898/2026.01.19.699752

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