Article
Oligodendrocyte Development and Myelination in Neurodevelopment: Molecular Mechanisms in Health and Disease
27 Jan 2016
Abstract excerpt
Oligodendrocytes are the myelinating cells of the central nervous system that constitute about 5 to 10% of the total glial population. These cells are responsible for myelin sheath production, which is essential not only for the rapid and efficient conduction of the electrical impulses along the axons, but also for preserving axonal integrity. Oligodendrocytes arise from oligodendrocyte progenitor cells that...
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