Article

Delayed maturation of inner hair cell ribbon synapses in a mouse model of fragile X syndrome

2025-04-01

Abstract excerpt

Clinical features of FXS phenotype include intellectual disability, repetitive behaviors, social communication deficit and also commonly manifested auditory hypersensitivity for acoustic stimuli. The electrophysiological studies have shown that FXS patients and Fmr1 KO mice display improper processing of auditory information in the cortical areas of the brain and the spiral ganglion of cochlea. Synapses formed by...

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Literature Corpus work: 7ab2bf4e-0191-5514-8a6b-ad367ec49b52
DOI: 10.1101/2025.03.31.646200

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