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Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

2023-07-15

Abstract excerpt

<h4>ABSTRACT</h4> Reactive oxygen species (ROS) are a double-edge sword in cancers and can both promote pro-tumorigenic signaling and also trigger oxidative stress dependent cell death. Thus, maintaining redox homeostasis to control levels of ROS within a tumor-promoting range elicits critical tumorigenic potential in cancer. Here, we show that head and neck squamous cell carcinoma (HNSCC) is uniquely characteriz...

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Literature Corpus work
7aa06a29-2ef1-57ad-be60-4a65dce6d009
DOI
10.1101/2023.07.13.548944
Open publication

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Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growthDOI 10.1101/2023.07.13.548944
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