Altered metabolism in head and neck squamous cell carcinoma: an opportunity for identification of novel biomarkers and drug targets.

Abstract excerpt

Tumor cells were first shown to exhibit a distinct metabolic phenotype over 80 years ago. Since then, it has become clear that multiple oncogenic events contribute to the development of a metabolic phenotype that supports rapid proliferation. Because this phenotype represents an essential component of tumorigenesis and disease progression, it also represents a potential source of biomarkers associated with...

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