Article

Tobacco smoke exposure is a driver of altered oxidative stress response and immunity in head and neck cancer

2024-10-21

Abstract excerpt

<h4>Purpose</h4> Exposomes are critical drivers of carcinogenesis. However, how they modulate tumor behavior remains unclear. Extensive clinical data link cigarette smoke as a key exposome that promotes aggressive tumors, higher rates of metastasis, reduced response to chemoradiotherapy, and suppressed anti-tumor immunity. We sought to determine whether smoke itself can modulate aggressive tumor behavior in head...

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Identifiers and source

Literature Corpus work: 69e32720-c36b-5131-a755-831ca24047f8
DOI: 10.1101/2024.10.17.618907

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