Article

Engineered histones reshape chromatin in human cells

2025-09-11

Abstract excerpt

Histone proteins and their variants have been found to play crucial and specialized roles in chromatin organization and the regulation of downstream gene expression; however, the relationship between histone sequence and its effect on chromatin organization remains poorly understood, limiting our functional understanding of sequence variation between distinct subtypes and across evolution and frustrating efforts t...

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Literature Corpus work: 7a9c4b14-6369-59a3-86cf-9e9c789982a7
DOI: 10.1101/2025.09.10.674980

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