Article

Remote neuronal activity drives glioma infiltration via Sema4f

2023-03-16

Abstract excerpt

The tumor microenvironment (TME) plays an essential role in malignancy and neurons have emerged as a key component of the TME that promotes tumorigenesis across a host of cancers. Recent studies on glioblastoma (GBM) highlight bi-directional signaling between tumors and neurons that propagates a vicious cycle of proliferation, synaptic integration, and brain hyperactivity; however, the identity of neuronal subtype...

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Literature Corpus work: 1a123cb2-a2bd-5458-ad5f-0011221f5222
DOI: 10.1101/2023.03.15.532832

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