Article

Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9

2020-12-28

Abstract excerpt

<h4>Summary</h4> Autophagy is a cellular degradation pathway essential for neuronal health and function. Autophagosome biogenesis occurs at synapses, is locally regulated and increases in response to neuronal activity. The mechanisms that couple autophagosome biogenesis to synaptic activity remain unknown. In this study we determine that trafficking of ATG-9, the only transmembrane protein in the core autophagy p...

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Literature Corpus work: caee69bd-f824-55c9-8ca4-a4ca9102813f
DOI: 10.1101/2020.12.28.424508

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