Article

A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in <i>Drosophila</i> secondary cells

2023-04-04

Abstract excerpt

Secretory cells in glands and the nervous system frequently package and store proteins destined for regulated secretion in dense-core granules (DCGs), which disperse when released from the cell surface. Despite the relevance of this dynamic process to diseases such as diabetes and human neurodegenerative disorders, our mechanistic understanding is relatively limited, because of the lack of good cell models to foll...

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Literature Corpus work: d08ddac6-2c4b-56bf-ad33-056f34bdbd2a
DOI: 10.1101/2023.04.04.535541

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