Article

The ability of human TIM1 to bind phosphatidylethanolamine enhances viral uptake and efferocytosis compared to rhesus and mouse orthologs

2024-07-29

Abstract excerpt

<h4>ABSTRACT</h4> T-cell Immunoglobulin and Mucin (TIM)-family proteins facilitate the clearance of apoptotic cells, are involved in immune regulation, and promote infection of enveloped viruses. These processes are frequently studied in experimental animals such as mice or rhesus macaques, but functional differences among the TIM orthologs from these species have not been described. Previously, we reported that...

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Literature Corpus work: 7a50d8b9-38b3-52a8-9b30-7aa2f510b806
DOI: 10.1101/2024.07.29.605603

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