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Article

TIM-1 Promotes Japanese Encephalitis Virus Entry and Infection

14 Nov 2018

Abstract excerpt

, the leading cause of viral-induced encephalitis. Several host molecules have been identified as the JEV attachment factor; however, the molecules involved in JEV entry remain poorly understood. In the present study, we demonstrate that TIM-1 is important for efficient infection by JEV. Firstly, three TIM-1 variants (V1, V2, and V3) were cloned from A549 cells, and we revealed that only ectopically TIM-1 V2...

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PMID: 30441759
DOI: 10.3390/v10110630

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