Article

Ciliary tip actin dynamics regulate the cadence of photoreceptor disc formation

2022-11-11

Abstract excerpt

As signalling organelles, primary cilia regulate their membrane G protein-coupled receptor (GPCR) content by ectocytosis, a process requiring localised actin dynamics at their tip to alter membrane shape.(1, 2) Mammalian photoreceptor outer segments comprise an expanse of folded membranes (discs) at the tip of highly-specialised connecting cilia (CC), in which photosensitive GPCRs like rhodopsin are concentrated....

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Literature Corpus work: 7a1aa1da-196f-5a2a-a0a9-d5bb51f34f7d
DOI: 10.1101/2022.11.10.516020

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