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Article

The ciliary rootlet maintains long-term stability of sensory cilia.

Molecular and cellular biology - 1 May 2005

Yang Jun, Gao Jiangang, Adamian Michael, Wen Xiao-Hong, Pawlyk Basil, Zhang Luo, Sanderson Michael J, Zuo Jian, Makino Clint L, Li Tiansen

Abstract excerpt

The striated ciliary rootlet is a prominent cytoskeleton originating from basal bodies of ciliated cells. Although a familiar structure in cell biology, its function has remained unresolved. In this study, we carried out targeted disruption in mice of the gene for rootletin, a component of the rootlet. In the mutant, ciliated cells are devoid of rootlets. Phototransduction and ciliary beating in sensory and...

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Identifiers

PMID: 15870283
DOI: 10.1128/MCB.25.10.4129-4137.2005
PMCID: PMC1087714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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