Article

RPGR regulates motile cilia by interfering with actin dynamics

2025-03-14

Abstract excerpt

Cilia are highly conserved cellular organelles extruding from the surface of cell types carrying either sensory (signaling) or motile functions. These include photoreceptor cells and airway epithelia, where they function in light sensation and mucociliary clearance respectively. Retinitis pigmentosa GTPase regulator ( RPGR ) variants affect both photoreceptor sensory cilia and airway motile cilia, leading to reti...

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Literature Corpus work: 4022cbc5-a842-5c4f-88db-0a7f4ce6eed3
DOI: 10.1101/2025.03.13.643176

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